BDBM50265918 3-(4-((4-tert-butylphenyl)ethynyl)phenyl)-1,2,4-oxadiazol-5(4H)-one::CHEMBL511855

SMILES CC(C)(C)c1ccc(cc1)C#Cc1ccc(cc1)-c1nc(=O)o[nH]1

InChI Key InChIKey=GPGOTYXSTNCOBN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265918   

TargetRetinoic acid receptor beta(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50265918(3-(4-((4-tert-butylphenyl)ethynyl)phenyl)-1,2,4-ox...)
Affinity DataEC50:  820nMAssay Description:Activity at human RARbeta ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50265918(3-(4-((4-tert-butylphenyl)ethynyl)phenyl)-1,2,4-ox...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at human RARalpha ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50265918(3-(4-((4-tert-butylphenyl)ethynyl)phenyl)-1,2,4-ox...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at human RARgamma ligand binding domain expressed in COS7 cells co-transfected with Gal4-DBD assessed as transcriptional activation after 16...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed