BDBM50266115 CHEMBL4075981

SMILES C[C@H](Oc1cc2oc(=O)n(CCC(O)=O)c2cc1Cl)c1ccccn1

InChI Key InChIKey=PVGOQRJICUIPTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266115   

TargetKynurenine 3-monooxygenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266115(CHEMBL4075981)
Affinity DataIC50: 251nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2020
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266115(CHEMBL4075981)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2020
Entry Details Article
PubMed