BDBM50266158 CHEMBL510225::Dimethyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-ethyl]-amine

SMILES CN(C)CCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1

InChI Key InChIKey=YLUJHHRCHJXUPR-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266158   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266158(Dimethyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-...)
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of of PTP1B assessed as residual enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266158(Dimethyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-...)
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of of PTP1B assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266158(Dimethyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-...)
Affinity DataKi:  2.51E+4nMAssay Description:Inhibition of of PTP1B assessed as residual enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266158(Dimethyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-...)
Affinity DataKi:  2.87E+4nMAssay Description:Inhibition of of PTP1B assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed