BDBM50266231 CHEMBL510460::Dimethyl-[3-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-propyl]-amine

SMILES CN(C)CCCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1

InChI Key InChIKey=DAJBZURMACAGTL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266231   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266231(Dimethyl-[3-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of of PTP1B assessed as residual enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266231(Dimethyl-[3-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-...)
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of of PTP1B assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266231(Dimethyl-[3-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-...)
Affinity DataKi:  3.41E+4nMAssay Description:Inhibition of of PTP1B assessed as residual enzyme activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266231(Dimethyl-[3-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-...)
Affinity DataKi:  3.63E+4nMAssay Description:Inhibition of of PTP1B assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed