BDBM50266497 CHEMBL4063923

SMILES OCc1cc2nc(nc(N3CCOCC3)c2s1)N1CCOc2ccccc12

InChI Key InChIKey=FDJMFUPBFCVPKM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266497   

TargetSerine/threonine-protein kinase mTOR(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50266497(CHEMBL4063923)Copy SMILESCopy InChI

Affinity DataIC50: 336nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) expressed in baculovirus infected Sf21 insect cells assessed as re...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/16/2020
Entry Details Article
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50266497(CHEMBL4063923)Copy SMILESCopy InChI

Affinity DataIC50: 681nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged PI3K p110alpha/p85alpha expressed in baculovirus using PIP2 as substrate after 1 hr...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/16/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL