BDBM50266561 CHEMBL4096633

SMILES COc1ccc(cc1OC)N(C)c1cnc(SCc2c(F)cc(cc2F)C#CC[N+](C)(C)C)n1-c1ccc(F)cc1

InChI Key InChIKey=LZTYXNALZMPMDG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266561   

TargetG-protein coupled bile acid receptor 1(Mouse)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50266561(CHEMBL4096633)
Affinity DataEC50:  17nMAssay Description:Agonist activity at mouse TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50266561(CHEMBL4096633)
Affinity DataEC50:  260nMAssay Description:Agonist activity at human TGR5 transfected in HEK293 cells assessed as cAMP accumulation after overnight incubation by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2020
Entry Details Article
PubMed