BDBM50266834 CHEMBL477640::N-[4-[[2-(2,4-Diamino-5-allyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino]-3-bromo-benzoyl]-L-glutamic acid

SMILES Nc1nc(N)c2N(CC=C)C(CNc3ccc(cc3Br)C(=O)NC(CCC(O)=O)C(O)=O)CCc2n1

InChI Key InChIKey=WDHACPDURGLUTQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266834   

TargetDihydrofolate reductase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50266834(N-[4-[[2-(2,4-Diamino-5-allyl-5,6,7,8-tetrahydropy...)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human recombinant DHFR by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed