BDBM50266836 CHEMBL477028::N-[4-[[2-(2,4-Diamino-5,10-diallyl-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamic acid

SMILES Nc1nc(N)c2N(CC=C)C(CN(CC=C)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)CCc2n1

InChI Key InChIKey=JYTSGRLKDGDPGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266836   

TargetDihydrofolate reductase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50266836(N-[4-[[2-(2,4-Diamino-5,10-diallyl-5,6,7,8-tetrahy...)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human recombinant DHFR by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed