BDBM50267027 CHEMBL4094160

SMILES OC(=O)C[C@@H]1C[C@@H](CN1c1ccc(Oc2ccccc2OC(F)(F)F)cc1)C(F)(F)F

InChI Key InChIKey=TVXOVCKZHVNQJQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267027   

TargetFree fatty acid receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267027(CHEMBL4094160)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267027(CHEMBL4094160)
Affinity DataEC50:  740nMAssay Description:Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed