BDBM50267272 6-(2-Fluoropropyl)-4-methylpyridin-2-amine::CHEMBL450726

SMILES CC(F)Cc1cc(C)cc(N)n1

InChI Key InChIKey=MBHRCNFCHFHUKZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267272   

TargetNitric oxide synthase, inducible(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50267272(6-(2-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant iNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50267272(6-(2-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant nNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50267272(6-(2-Fluoropropyl)-4-methylpyridin-2-amine | CHEMB...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant eNOS using 1 mM NADH and 2 uM L-arginine after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed