BDBM50268224 2-(6-Amino-7H-purine-7-yl)-1-(1H-indole-3-yl)ethanone::CHEMBL485246

SMILES Nc1ncnc2ncn(CC(=O)c3c[nH]c4ccccc34)c12

InChI Key InChIKey=XGLISBDQVHVZBR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50268224   

TargetVascular endothelial growth factor receptor 2(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268224(2-(6-Amino-7H-purine-7-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268224(2-(6-Amino-7H-purine-7-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268224(2-(6-Amino-7H-purine-7-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50268224(2-(6-Amino-7H-purine-7-yl)-1-(1H-indole-3-yl)ethan...)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed