BDBM50268267 CHEMBL4083291

SMILES Fc1ncc(Cn2c3ccccc3c(=O)[nH]c2=O)cc1NC(=O)[C@H]1CCN(CCC(F)(F)F)C1

InChI Key InChIKey=LLBQUOHKCAYWBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268267   

TargetPoly [ADP-ribose] polymerase 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50268267(CHEMBL4083291)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human PARP-2 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50268267(CHEMBL4083291)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant human PARP-1 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed