BDBM50268284 CHEMBL4100719

SMILES Fc1ncc(Cn2c3ccccc3c(=O)[nH]c2=O)cc1NC(=O)[C@H]1CCN(C1)c1ccccc1

InChI Key InChIKey=BSBYIGMCJVUHQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268284   

TargetPoly [ADP-ribose] polymerase 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50268284(CHEMBL4100719)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human PARP-2 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50268284(CHEMBL4100719)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human PARP-1 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed