BDBM50268285 CHEMBL4092324

SMILES CC(C)(C)OC(=O)N1CC[C@@H](C1)C(=O)Nc1cc(Cn2c3ccccc3c(=O)[nH]c2=O)cnc1F

InChI Key InChIKey=ZZFIQKPNOYYXIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268285   

TargetPoly [ADP-ribose] polymerase 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50268285(CHEMBL4092324)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant human PARP-2 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50268285(CHEMBL4092324)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human PARP-1 expressed in Escherichia coli BL21 (DE3) using sheared DNA as substrate in presence of biotinylated NAD after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed