BDBM50269460 CHEMBL4061578

SMILES COc1cccc(c1)C1CN(CCN1)c1nc(cc(=O)n1C)-c1ccncc1

InChI Key InChIKey=BOVSPBWFWORURG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50269460   

TargetGlycogen synthase kinase-3 beta(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269460(CHEMBL4061578)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269460(CHEMBL4061578)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269460(CHEMBL4061578)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269460(CHEMBL4061578)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed