BDBM50269465 CHEMBL4078436

SMILES COc1ccc(cc1)C1CN(CCN1)c1nc(cc(=O)n1C)-c1ccncc1

InChI Key InChIKey=UJEZKRJUBHZWII-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50269465   

TargetGlycogen synthase kinase-3 beta(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269465(CHEMBL4078436)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant human GSK-3beta using prephosphorylated GS-1 peptide as substrate after 1 hr in presence of [gamma-32P]ATP by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269465(CHEMBL4078436)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269465(CHEMBL4078436)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50269465(CHEMBL4078436)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2020
Entry Details Article
PubMed