BDBM50269929 (2S,5S)-2-Hydroxymethyl-5-[1'-2'-(2''-naphtyl)}-ethynyl]-1-aza-bicyclo-[2.2.2]-octane::CHEMBL517050

SMILES OC[C@@H]1CC2CCN1C[C@@H]2C#Cc1ccc2ccccc2c1

InChI Key InChIKey=TWIMLFNHIWESPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269929   

TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50269929((2S,5S)-2-Hydroxymethyl-5-[1'-2'-(2''-naphtyl)}-et...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed