BDBM50269930 (2R,5S)-2-Hydroxymethyl-5-[1'-2'-(2''-quinolyl)}-ethynyl]-1-aza-bicyclo-[2.2.2]-octane::CHEMBL477322

SMILES OC[C@H]1CC2CCN1C[C@@H]2C#Cc1cnc2ccccc2c1

InChI Key InChIKey=NCFADVGMVIJELQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269930   

TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50269930((2R,5S)-2-Hydroxymethyl-5-[1'-2'-(2''-quinolyl)}-e...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed