BDBM50269945 CHEMBL4092221

SMILES COc1ccc(C=CC2=NN(CCCCN)C(=O)N(Cc3ccc4ccccc4c3)c3ccccc23)cc1

InChI Key InChIKey=NKZTVWHDNWNDGG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269945   

TargetUrotensin-2 receptor(Rat)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50269945(CHEMBL4092221)
Affinity DataEC50:  3.60nMAssay Description:Allosteric modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aorta assessed as change in human urotensin-2-mediated aortic ring contr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Rat)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50269945(CHEMBL4092221)
Affinity DataEC50:  8.5nMAssay Description:Allosteric modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aorta assessed as change in URP-mediated aortic ring contraction by meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2020
Entry Details Article
PubMed