BDBM50270400 CHEMBL363360

SMILES COc1ccc(CC2c3cc(OC)c(OC)cc3CC[N+]2(C)C)cc1OC

InChI Key InChIKey=RVBHVIRGZXRPRX-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50270400   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270400(CHEMBL363360)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270400(CHEMBL363360)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270400(CHEMBL363360)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270400(CHEMBL363360)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270400(CHEMBL363360)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed