BDBM50270748 CHEMBL4125968

SMILES O=C(Nc1c(C#N)c(c(-c2ccccc2)n1Cc1ccccc1)-c1ccccc1)c1ccccc1

InChI Key InChIKey=QHUOQDLACSDLMI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270748   

TargetMetallo-beta-lactamase AIM-1(Pseudomonas aeruginosa)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50270748(CHEMBL4125968)
Affinity DataKi:  1.60E+3nMAssay Description:Competitive inhibition of Pseudomonas aeruginosa recombinant AIM1 expressed in Escherichia coli BL21(DE3) using cefuroxime as substrate by UV/Vis mul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50270748(CHEMBL4125968)
Affinity DataKi:  9.00E+3nMAssay Description:Competitive inhibition of NDM-1 (unknown origin) using penicillin G as substrate by Michaelis-Menten equation based kinetic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetMetallo-beta-lactamase type 2(Aeromonas hydrophila)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50270748(CHEMBL4125968)
Affinity DataKi:  1.10E+4nMAssay Description:Competitive inhibition of Aeromonas hydrophila recombinant CphA expressed in Escherichia coli BL21(DE3) using meropenem as substrate by UV/Vis multi-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed