BDBM50271657 CHEMBL4128513

SMILES COc1ccc(cc1C)-c1csc(Nc2ccc(O)c(c2)C(O)=O)n1

InChI Key InChIKey=JKAHVAHFZKSBFC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271657   

TargetProtein arginine N-methyltransferase 5(Human)
University of Jinan

Curated by ChEMBL
LigandPNGBDBM50271657(CHEMBL4128513)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandPNGBDBM50271657(CHEMBL4128513)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
University of Jinan

Curated by ChEMBL
LigandPNGBDBM50271657(CHEMBL4128513)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged CARM1 (2 to end residues) expressed in HEK293F cells pretreated for 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
University of Jinan

Curated by ChEMBL
LigandPNGBDBM50271657(CHEMBL4128513)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PRMT1 (2 to end residues) expressed in baculovirus infected Sf9 insect cells using peptide subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed