BDBM50271894 CHEMBL500921::N1-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenyl)-N3-(4-fluorophenyl)malonamide

SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)cc1

InChI Key InChIKey=PLLLNZXGUXHIHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271894   

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50271894(N1-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorop...)
Affinity DataIC50: 64nMAssay Description:Inhibition of Met kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50271894(N1-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorop...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed