BDBM50272170 CHEMBL500937::H-Dmt-Tic-Gly-N(Me)-Ph

SMILES CN(C(=O)CNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1

InChI Key InChIKey=CADRNJIFUDEZBB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272170   

TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272170(H-Dmt-Tic-Gly-N(Me)-Ph | CHEMBL500937)
Affinity DataKi:  0.143nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272170(H-Dmt-Tic-Gly-N(Me)-Ph | CHEMBL500937)
Affinity DataKi:  1.75nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50272170(H-Dmt-Tic-Gly-N(Me)-Ph | CHEMBL500937)
Affinity DataIC50: 1.47E+3nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed