BDBM50272221 CHEMBL4128512

SMILES Cc1ccc(cc1)S(=O)(=O)NC(CCc1ccccc1)C(=O)Nc1ccc(cc1)C(N)=N

InChI Key InChIKey=IWMPEGNVEXTCDL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272221   

TargetSerine protease hepsin(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272221(CHEMBL4128512)
Affinity DataIC50: 870nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272221(CHEMBL4128512)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272221(CHEMBL4128512)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272221(CHEMBL4128512)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed