BDBM50272377 (1S,9R,10S)-4-(4-aminophenoxy)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-10-ol hydrochloride::CHEMBL499868

SMILES Nc1ccc(Oc2ccc3C[C@H]4N(CC5CCC5)CC[C@@]5(CCCC[C@@]45O)c3c2)cc1

InChI Key InChIKey=HHYBRMOEHYGPAR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272377   

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50272377((1S,9R,10S)-4-(4-aminophenoxy)-17-(cyclobutylmethy...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50272377((1S,9R,10S)-4-(4-aminophenoxy)-17-(cyclobutylmethy...)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50272377((1S,9R,10S)-4-(4-aminophenoxy)-17-(cyclobutylmethy...)
Affinity DataKi:  930nMAssay Description:Displacement of [3H]Naltindole from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed