BDBM50272648 CHEMBL523574::N-methyl((3R,4R)-4-(o-tolyloxy)thiochroman-3-yl)methanamine

SMILES CNC[C@H]1CSc2ccccc2[C@@H]1Oc1ccccc1C

InChI Key InChIKey=PXFCLZUOFIJVNC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272648   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272648(N-methyl((3R,4R)-4-(o-tolyloxy)thiochroman-3-yl)me...)
Affinity DataIC50: 430nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272648(N-methyl((3R,4R)-4-(o-tolyloxy)thiochroman-3-yl)me...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50272648(N-methyl((3R,4R)-4-(o-tolyloxy)thiochroman-3-yl)me...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed