BDBM50272735 CHEMBL4126958

SMILES COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3cccc4nc5CCCCc5c(N)c34)c2c1

InChI Key InChIKey=PLBJUXNUAHLGTD-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272735   

Target5-hydroxytryptamine receptor 1A(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50272735(CHEMBL4126958)
Affinity DataEC50: <0.140nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells after 60 mins by Eu-cAMP solution based ultra LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50272735(CHEMBL4126958)
Affinity DataIC50: 400nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate after 20 mins by by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50272735(CHEMBL4126958)
Affinity DataIC50: 229nMAssay Description:Inhibition of SERT (unknown origin) expressed in HEK293 cells assessed as reduction in 5-HT uptake incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50272735(CHEMBL4126958)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate after 20 mins by by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed