BDBM50272761 2-(3''-Hydroxyphenyl)-4-(3'-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepine::CHEMBL508510

SMILES Oc1cccc(c1)C1CC(=Nc2ccccc2S1)c1cccc(O)c1

InChI Key InChIKey=HAWJYJKVVJPFCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272761   

TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50272761(2-(3''-Hydroxyphenyl)-4-(3'-hydroxyphenyl)-2,3-dih...)
Affinity DataIC50: 7.11E+4nMAssay Description:Inhibition of Electrophorus electricus (electric eel) acetylcholinesterase (AChE) using acetylthiocholine iodide as substrate preincubated for 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

TargetCholinesterase(Human)TBA
LigandPNGBDBM50272761(2-(3''-Hydroxyphenyl)-4-(3'-hydroxyphenyl)-2,3-dih...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

TargetCholinesterase(Human)TBA
LigandPNGBDBM50272761(2-(3''-Hydroxyphenyl)-4-(3'-hydroxyphenyl)-2,3-dih...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of BchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50272761(2-(3''-Hydroxyphenyl)-4-(3'-hydroxyphenyl)-2,3-dih...)
Affinity DataIC50: 7.11E+4nMAssay Description:Inhibition of AchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed