BDBM50272802 2-(4''-N,N-Dimethylamino)-4-(3'-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepine::CHEMBL508471

SMILES CN(C)c1ccc(cc1)C1CC(=Nc2ccccc2S1)c1cccc(O)c1

InChI Key InChIKey=BHIYBBZCRKSVSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272802   

TargetCholinesterase(Human)TBA
LigandPNGBDBM50272802(2-(4''-N,N-Dimethylamino)-4-(3'-hydroxyphenyl)-2,3...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

TargetCholinesterase(Human)TBA
LigandPNGBDBM50272802(2-(4''-N,N-Dimethylamino)-4-(3'-hydroxyphenyl)-2,3...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of BChE (unknown origin) using BCh iodide as substrate preincubated for 15 mins prior to substrate addition measured after 10 mins by Ellm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCholinesterase(Human)TBA
LigandPNGBDBM50272802(2-(4''-N,N-Dimethylamino)-4-(3'-hydroxyphenyl)-2,3...)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of BchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed