BDBM50272839 2-(Thien-2''-yl)-4-(3'-hydroxyphenyl)-2,3-dihydro-1,5-benzothiazepine::CHEMBL498536

SMILES Oc1cccc(c1)C1=Nc2ccccc2SC(C1)c1cccs1

InChI Key InChIKey=RPBZUFRIXGCULF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50272839   

TargetCholinesterase(Human)TBA
LigandPNGBDBM50272839(2-(Thien-2''-yl)-4-(3'-hydroxyphenyl)-2,3-dihydro-...)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

TargetAcetylcholinesterase(Electric eel)TBA
LigandPNGBDBM50272839(2-(Thien-2''-yl)-4-(3'-hydroxyphenyl)-2,3-dihydro-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of Electrophorus electricus (electric eel) acetylcholinesterase (AChE) using acetylthiocholine iodide as substrate preincubated for 15 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

TargetCholinesterase(Human)TBA
LigandPNGBDBM50272839(2-(Thien-2''-yl)-4-(3'-hydroxyphenyl)-2,3-dihydro-...)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of BChE (unknown origin) using BCh iodide as substrate preincubated for 15 mins prior to substrate addition measured after 10 mins by Ellm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50272839(2-(Thien-2''-yl)-4-(3'-hydroxyphenyl)-2,3-dihydro-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of AchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)TBA
LigandPNGBDBM50272839(2-(Thien-2''-yl)-4-(3'-hydroxyphenyl)-2,3-dihydro-...)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of BchEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed