BDBM50273093 CHEMBL457196::ethyl 2-methyl-3-oxo-6-(1-(3,4,5-trifluorophenyl)piperidine-4-carboxamido)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylate

SMILES CCOC(=O)C1(C)Oc2ccc(NC(=O)C3CCN(CC3)c3cc(F)c(F)c(F)c3)cc2NC1=O

InChI Key InChIKey=CYBXWNVHDIVVDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273093   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50273093(ethyl 2-methyl-3-oxo-6-(1-(3,4,5-trifluorophenyl)p...)
Affinity DataIC50: 870nMAssay Description:Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed