BDBM50273457 (R)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydroxypropan-2-yl)-5-methylthiazol-4(5H)-one::CHEMBL456539

SMILES C[C@H](NC1=NC(=O)[C@](C)(S1)C(C)(C)O)c1ccc(F)cc1

InChI Key InChIKey=HYVZYASDRIAOPU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273457   

LigandPNGBDBM50273457((R)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataKi:  210nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50273457((R)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed