BDBM50273533 CHEMBL4126784::US11535607, Example 50-2

SMILES ONC(=O)c1cccc2CN(CCc12)c1nc2ccccc2[nH]1

InChI Key InChIKey=MJBVGWCISSIYKJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50273533   

TargetHistone deacetylase 11(Human)
Valo Health

US Patent
LigandPNGBDBM50273533(CHEMBL4126784 | US11535607, Example 50-2)
Affinity DataIC50: 750nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Valo Health

US Patent
LigandPNGBDBM50273533(CHEMBL4126784 | US11535607, Example 50-2)
Affinity DataIC50: 1.00E+3nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Valo Health

US Patent
LigandPNGBDBM50273533(CHEMBL4126784 | US11535607, Example 50-2)
Affinity DataIC50: 1.00E+3nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Valo Health

US Patent
LigandPNGBDBM50273533(CHEMBL4126784 | US11535607, Example 50-2)
Affinity DataIC50: 1.00E+3nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Valo Health

US Patent
LigandPNGBDBM50273533(CHEMBL4126784 | US11535607, Example 50-2)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Valo Health

US Patent
LigandPNGBDBM50273533(CHEMBL4126784 | US11535607, Example 50-2)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length recombinant human HDAC6 using fluorescent-labeled peptide as substrate by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed