BDBM50273534 CHEMBL4127829::US11535607, Example 1-2

SMILES Cc1nc([nH]c1C)N1Cc2cccc(C(=O)NO)c2C1

InChI Key InChIKey=APXXOQCOOOYNJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273534   

TargetHistone deacetylase 11(Human)
Valo Health

US Patent
LigandPNGBDBM50273534(CHEMBL4127829 | US11535607, Example 1-2)
Affinity DataIC50: 1.00E+3nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Valo Health

US Patent
LigandPNGBDBM50273534(CHEMBL4127829 | US11535607, Example 1-2)
Affinity DataIC50: 1.00E+3nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Valo Health

US Patent
LigandPNGBDBM50273534(CHEMBL4127829 | US11535607, Example 1-2)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2020
Entry Details Article
PubMed