BDBM50273574 2-Cyclohexyl-1-[4-difluoromethoxy-3-(tetrahydrofuran-3-yloxy)phenyl]ethanone::CHEMBL458932

SMILES FC(F)Oc1ccc(cc1OC1CCOC1)C(=O)CC1CCCCC1

InChI Key InChIKey=HRACJZOSAUAQQQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273574   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273574(2-Cyclohexyl-1-[4-difluoromethoxy-3-(tetrahydrofur...)
Affinity DataIC50: 661nMAssay Description:Inhibition of full length human PDE4D2 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50273574(2-Cyclohexyl-1-[4-difluoromethoxy-3-(tetrahydrofur...)
Affinity DataIC50: 661nMAssay Description:Inhibition of full length human PDE4D2 expressed in Escherichia coli BL21 by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50273574(2-Cyclohexyl-1-[4-difluoromethoxy-3-(tetrahydrofur...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed