BDBM50273676 6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalen-2-ol::CHEMBL461458

SMILES OC1CCc2cc(ccc2C1)-c1cccnc1

InChI Key InChIKey=ROYVUWJYYRTBSK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273676   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273676(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalen-2-ol |...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273676(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalen-2-ol |...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273676(6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalen-2-ol |...)
Affinity DataIC50: 4.92E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed