BDBM50273677 3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyridine::CHEMBL460178

SMILES COC1CCc2cc(ccc2C1)-c1cccnc1

InChI Key InChIKey=LPKACSKZPXNEBK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50273677   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human recombinant CYP3A4 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273677(3-(6-Methoxy-5,6,7,8-tetrahydronaphthalen-2-yl)pyr...)
Affinity DataIC50: 4.74E+4nMAssay Description:Inhibition of human recombinant CYP2B6 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed