BDBM50273700 6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitrile::CHEMBL461884

SMILES N#CC1=Cc2ccc(cc2CC1)-c1cccnc1

InChI Key InChIKey=ABEYVGWQDFHEFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273700   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273700(6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitri...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273700(6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitri...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273700(6-Pyridin-3-yl-3,4-dihydronaphthalene-2-carbonitri...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed