BDBM50273778 8-Chloro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-one::CHEMBL457640

SMILES Clc1cc(cc2CCC(=O)Nc12)-c1cccnc1

InChI Key InChIKey=LNWWJGFDKHJMCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273778   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273778(8-Chloro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273778(8-Chloro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-...)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50273778(8-Chloro-6-pyridin-3-yl-3,4-dihydroquinolin-2(1H)-...)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of human recombinant CYP1A2 expressed in baculovirus-infected insect microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed