BDBM50273980 CHEMBL4127236::US11859014, Compound 39
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C[C@@H]1CCCNC1=O)C(=O)C(F)(F)F
InChI Key InChIKey=XFEMJBWUXOSMGT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50273980
TargetGenome polyprotein(Norovirus Hu/GII.4-2002/WeertE022/2002/NL)
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of Norovirus prototypic GII.4 3CL protease using HiLyte Fluor 488-labelled DFELQGPK as substrate incubated for 90 mins measured every mins...More data for this Ligand-Target Pair
Affinity DataIC50: 654nMAssay Description:Inhibition of Norovirus prototypic GI.1 3CL protease using HiLyte Fluor 488-labelled DFELQGPK as substrate incubated for 90 mins measured every mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of these compounds to inhibit the NoV, specifically Minerva virus protease catalytic Cys139 covalently (IC50 and Ki) was determined with ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The ability of these compounds to inhibit the NoV, specifically Minerva virus protease catalytic Cys139 covalently (IC50 and Ki) was determined with ...More data for this Ligand-Target Pair