BDBM50274242 4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}-amino)-7-[(1E)-3-pyrrolidin-1-ylprop-1-enyl]quinoline-3-carbonitrile::CHEMBL521013

SMILES Cn1ccnc1Sc1ccc(Nc2c(cnc3cc(\C=C\CN4CCCC4)ccc23)C#N)cc1Cl

InChI Key InChIKey=KJIKEFFIRMLEEQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274242   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth Research

Curated by ChEMBL

LigandBDBM50274242(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)Copy SMILESCopy InChI

Affinity DataIC50: 59nMAssay Description:Inhibition of MEK1 by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2010
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