BDBM50274440 4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}-amino)-6-methoxy-7-[(1E)-5-(4-methylpiperazin-1-yl)pent-1-enyl]quinoline-3-carbonitrile::CHEMBL450271

SMILES COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(cnc2cc1\C=C\CCCN1CCN(C)CC1)C#N

InChI Key InChIKey=RXUVBDZGTGQFMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274440   

LigandPNGBDBM50274440(4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]ph...)
Affinity DataIC50: 6nMAssay Description:Inhibition of MEK1 by raf/MEK1/MAPK coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed