BDBM50274461 CHEMBL504587::FGGFTGARKSARKWANQ

SMILES C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccccc2)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O

InChI Key InChIKey=MRPJNGQFWWZSQY-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274461   

TargetNociceptin receptor(Rat)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50274461(FGGFTGARKSARKWANQ | CHEMBL504587)
Affinity DataIC50: 0.410nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50274461(FGGFTGARKSARKWANQ | CHEMBL504587)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50274461(FGGFTGARKSARKWANQ | CHEMBL504587)
Affinity DataIC50: 0.410nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50274461(FGGFTGARKSARKWANQ | CHEMBL504587)
Affinity DataEC50:  5.80nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed