BDBM50274564 8-Fluoro-3-[[4-(5-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide::CHEMBL485034

SMILES CCCN(CCCCn1ccc2cc(F)ccc12)C1COc2c(F)ccc(C(N)=O)c2C1

InChI Key InChIKey=UVAUNLUVSFGRMF-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50274564   

Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274564(8-Fluoro-3-[[4-(5-fluoro-1H-indol-1-yl)butyl](prop...)
Affinity DataKi:  6.54nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274564(8-Fluoro-3-[[4-(5-fluoro-1H-indol-1-yl)butyl](prop...)
Affinity DataKi:  114nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in Sprague-Dawley rat frontal cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50274564(8-Fluoro-3-[[4-(5-fluoro-1H-indol-1-yl)butyl](prop...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-HT transporter-mediated [3H]5HT uptake in human Jar cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed