BDBM50274767 CHEMBL4125735

SMILES Clc1cccc(c1)S(=O)(=O)n1ccc2c(N[C@H]3CCNC3)nc3ccccc3c12

InChI Key InChIKey=SNVFALINPNEXRI-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50274767   

TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50274767(CHEMBL4125735)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant MAO-B using p-tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50274767(CHEMBL4125735)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]LSD from human 5-HT6R expressed in HEK293 cell membranes after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50274767(CHEMBL4125735)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50274767(CHEMBL4125735)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50274767(CHEMBL4125735)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R stably expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50274767(CHEMBL4125735)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr by Microbeta ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed