BDBM50275107 CHEMBL4130303

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)NCCSSCCNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O

InChI Key InChIKey=DQAHFXNORWIJPU-UHFFFAOYSA-N

Data  6 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50275107   

TargetMu-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataKi:  0.269nMAssay Description:Displacement of [3H]DAMGO from MOR (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]DAMGO from MOR (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]DADLE from DOR (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]DADLE from DOR (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataKi:  0.870nMAssay Description:Displacement of [3H]U69593 from KOR (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataKi:  0.871nMAssay Description:Displacement of [3H]U69593 from KOR (unknown origin) expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at DOR (unknown origin) expressed in HEK cells assessed as reduction in cAMP accumulation by split luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at DOR (unknown origin) expressed in HEK cells assessed as reduction in cAMP accumulation by split luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at MOR (unknown origin) expressed in HEK cells assessed as reduction in cAMP accumulation by split luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at MOR (unknown origin) expressed in HEK cells assessed as reduction in cAMP accumulation by split luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataEC50:  13nMAssay Description:Agonist activity at KOR (unknown origin) expressed in HEK cells assessed as reduction in cAMP accumulation by split luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50275107(CHEMBL4130303)
Affinity DataEC50:  14nMAssay Description:Agonist activity at KOR (unknown origin) expressed in HEK cells assessed as reduction in cAMP accumulation by split luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed