BDBM50275305 3-((2,2-Dimethylazetidine-1-carbonyloxy)-1-methylpropyl)dimethylammonium Oxalate::CHEMBL528765

SMILES CC(CCOC(=O)N1CCC1(C)C)N(C)C

InChI Key InChIKey=QLPIWKCAQGXORE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50275305   

TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275305(3-((2,2-Dimethylazetidine-1-carbonyloxy)-1-methylp...)
Affinity DataKi:  51nMAssay Description:Agonist activity at rat alpha-3-beta-4 nAChR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275305(3-((2,2-Dimethylazetidine-1-carbonyloxy)-1-methylp...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]epibatidine from rat recombinant alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275305(3-((2,2-Dimethylazetidine-1-carbonyloxy)-1-methylp...)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]epibatidine from rat recombinant alpha-4-beta-4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275305(3-((2,2-Dimethylazetidine-1-carbonyloxy)-1-methylp...)
Affinity DataKi:  2.50E+4nMAssay Description:Displacement of [3H]epibatidine from rat recombinant alpha-3-beta-4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275305(3-((2,2-Dimethylazetidine-1-carbonyloxy)-1-methylp...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]MLA from rat alpha-7 nAChR/mouse 5HT3A chimera expressed in human tsA-201 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed