BDBM50275600 CHEMBL4128596

SMILES COc1cccc(CNc2nc(N)c3nc(sc3n2)-c2ccccc2)c1

InChI Key InChIKey=BCYGXPUZEWFUON-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50275600   

TargetAdenosine receptor A1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50275600(CHEMBL4128596)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-DPCPX from human A1 adenosine receptor expressed in CHO cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50275600(CHEMBL4128596)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at human A1 adenosine receptor expressed in CHO cells assessed as inhibition of CCPA-induced reduction of forskolin-stimulated cA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50275600(CHEMBL4128596)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-ZM 241,385 from human A2A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50275600(CHEMBL4128596)
Affinity DataIC50: 48nMAssay Description:Inverse agonist activity at human A2A adenosine receptor expressed in CHO cells assessed as inhibition of basal cAMP level after 30 mins by Alphascre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50275600(CHEMBL4128596)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at human A2A adenosine receptor expressed in CHO cells assessed as inhibition of CGS21680-stimulated cAMP level after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50275600(CHEMBL4128596)
Affinity DataIC50: 2.39E+3nMAssay Description:Antagonist activity at human A2B adenosine receptor assessed as inhibition of NECA-stimulated cAMP level after 30 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50275600(CHEMBL4128596)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]-ABMECA from human A3 adenosine receptor expressed in CHO cell membranes after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed