BDBM50275752 5-methyl-7-(3-(trifluoromethyl)phenyl)-N-(3,4,5-trimethoxyphenyl)imidazo[1,5-f][1,2,4]triazin-2-amine::CHEMBL520037

SMILES COc1cc(Nc2ncc3c(C)nc(-c4cccc(c4)C(F)(F)F)n3n2)cc(OC)c1OC

InChI Key InChIKey=FGUYNCHKIOFPMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275752   

TargetSerine/threonine-protein kinase PLK3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275752(5-methyl-7-(3-(trifluoromethyl)phenyl)-N-(3,4,5-tr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PLK3 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275752(5-methyl-7-(3-(trifluoromethyl)phenyl)-N-(3,4,5-tr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed